Hyperthermia siv cov cua kub sib txawv (xov tooj cua zaus, microwave, ultrasound, laser, thiab lwm yam) kom nce qhov kub ntawm cov qog nqaij hlav mus rau qhov kub thiab txias, ua rau cov qog hlwb tuag yam tsis muaj kev puas tsuaj rau lub cev.Hyperthermia tuaj yeem tsis tsuas yog rhuav tshem cov qog hlwb, tab sis tseem rhuav tshem qhov kev loj hlob thiab kev tsim tawm ib puag ncig ntawm cov qog hlwb.
Mechanism ntawm Hyperthermia
Cov qog nqaij hlav cancer, zoo li lwm cov hlwb, tau txais cov ntshav los ntawm cov hlab ntsha rau lawv txoj sia.
Txawm li cas los xij, cov qog nqaij hlav cancer tsis tuaj yeem tswj cov ntshav ntws hauv cov hlab ntsha, uas tau raug yuam hloov los ntawm lawv.Hyperthermia, ib txoj kev kho mob, capitalizes ntawm qhov tsis muaj zog ntawm cov qog nqaij hlav cancer.
1. Hyperthermia yog qhov thib tsib kev kho mob qog tom qab phais, kev kho mob hluav taws xob, tshuaj kho mob thiab biotherapy.
2. Nws yog ib qho tseem ceeb ntawm kev kho mob qog nqaij hlav (tuaj yeem ua ke nrog ntau yam kev kho mob los txhim kho kev kho mob ntawm cov qog).
3. Nws yog tsis muaj tshuaj lom, tsis mob, muaj kev nyab xeeb thiab tsis cuam tshuam, los yog kev kho ntsuab.
4. Ntau xyoo ntawm kev kho mob cov ntaub ntawv qhia tau hais tias kev kho mob zoo, tsis muaj kev cuam tshuam, rov qab sai, tsis tshua muaj kev pheej hmoo, thiab tus nqi qis rau cov neeg mob thiab tsev neeg (hnub tu hauv paus).
5. Txhua tus qog nqaij hlav hauv tib neeg tshwj tsis yog cov qog hlwb thiab qhov muag tuaj yeem kho tau (ib leeg, lossis ua ke nrog kev phais, xov tooj cua, tshuaj kho mob, qia cell, thiab lwm yam).
Cov qog cytoskeleton - ncaj qha ua rau cytoskeleton puas tsuaj.
Cov qog hlwb - hloov cov permeability ntawm cell membrane, pab txhawb kev nkag mus ntawm cov tshuaj chemotherapeutic, thiab ua tiav cov nyhuv ntawm kev txo toxicity thiab nce efficiency.
Nruab nrab nucleus.
Inhibition ntawm DNA thiab RNA polymerization ua rau kev loj hlob etiology thiab kev qhia ntawm cov khoom chromosomal proteins khi rau DNA thiab inhibition ntawm protein synthesis.
Cov hlab ntsha
inhibit qhov kev nthuav qhia ntawm qog-derived vascular endothelial kev loj hlob yam thiab nws cov khoom
