Raws li cov ntaub ntawv cuam tshuam ntawm Lub Chaw Haujlwm Saib Xyuas Kev Tshawb Fawb Thoob Ntiaj Teb rau Cancer (IARC) ntawm Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb (WHO), mob ntsws cancer tau dhau los ua ib qho ntawm cov qog nqaij hlav loj tshaj plaws, thiab kev tiv thaiv thiab kho mob ntsws cancer tau dhau los ua qhov tseem ceeb tshaj plaws. ntawm kev tiv thaiv thiab kho mob qog noj ntshav.
Raws li cov ntaub ntawv txheeb cais cuam tshuam, tsuas yog hais txog20% ntawm cov neeg mob qog nqaij hlav qog noj ntshav tsis yog me me tuaj yeem tau txais kev kho mob phais.Feem coob ntawm cov neeg mob qog nqaij hlav ntsws twb nyob hauvcov theem siab heevThaum kuaj pom, thiab lawv tuaj yeem tau txais txiaj ntsig tsawg los ntawm kev siv tshuaj tua hluav taws xob thiab tshuaj khomob.Nrog rau kev vam meej tas mus li thiab kev loj hlob ntawm kev kho mob science, qhov tshwm sim ntawmkev kho mob ablativeRaws li kev hloov pauv rau kev phais tau coj kev kho tshiab kev cia siab rau cov neeg mob qog noj ntshav.
1. Koj paub ntau npaum li cas txog kev kho mob ablative rau mob ntsws cancer?
Ablative therapy rau mob ntsws cancer feem ntau suav nrogmicrowave ablation thiab radiofrequency ablation.Lub hauv paus ntsiab lus kev kho mob suav nrog kev ntxig rau ablative electrode, tseem hu ua a"kev soj ntsuam,"nyob rau hauv lub qog nyob rau hauv lub ntsws.Cov electrode tuaj yeem ua rautxav ceevntawm cov khoom xws li ions lossis dej molecules nyob rau hauv cov qog, ua kom sov vim kev sib txhuam, ua rauirreversible puas xws li coagulative necrosis ntawm qog hlwb.Nyob rau tib lub sijhawm, qhov ceev ntawm cov cua kub hloov pauv sai sai hauv cov ntaub so ntswg ib puag ncig lub ntsws, khaws cia cov cua sov hauv cov qog, tsim kom muaj ib qho"thermal rwb thaiv tsev nyhuv."Ablative therapy tuaj yeem tua cov qog zoo thaum lub sijhawmmaximizing kev tiv thaiv ntawm lub ntsws li qub.
Ablative therapy yog tus cwj pwm los ntawm nwsrov ua dua, tsawg tus neeg mob tsis xis nyob, mob me me, thiab rov qab sai,thiab tau dav lees paub thiab siv hauv kev kho mob.Txawm li cas los xij, xav tias kev kho mob ablative muaj ntau yam kev qhuab qhia xws li hluav taws xob, oncology, kev cuam tshuam hluav taws xob, thiab kev phais lub cev, nws yuav tsum muaj kev phais siab thiab kev ua tau zoo los ntawm tus kws kho mob.
Niaj hnub no, peb xav qhia rau koj ib tug renowned kws muaj txuj nyob rau hauv lub teb ntawm interventional kev kho mob,Dr. Liu Chen, uas tau ua hauj lwm nyob rau hauv lub teb rau ntau xyoo thiab mob siab rau rau lub chaw kho mob translational kev tshawb fawb thiab standardized popularization ntawm minimally invasive interventional diagnostics thiab kev kho mob xws li nyuaj thiab muaj kev pheej hmoo qog nqaij hlav biopsies, thermal ablation, thiab particle implantation.Dr. Liu yog lub npe hu ua "tus phab ej ntawm rab koob" thiab tau koom nrog hauv kev tsim cov kws tshaj lij kev pom zoo thiab cov txheej txheem rau ntau yam kev kho mob rau kev mob ntsws cancer hauv Suav teb.Nws tau pioneered lub tswv yim ntawm kev tswj tag nrho ntawm lub ntsws cancer biopsies thiab tsim qauv txheej txheem kev phais los txhim kho kev txiav txim siab ntawm interventional kev kho mob nyob rau hauv lub zos kho mob rau lub ntsws cancer thaum ntxov, txhawb tag nrho cov kev loj hlob ntawm Tuam Tshoj txoj kev kuaj mob ntsws cancer thiab kev kho mob system.
"Hero on the Needle Tip" - Kws Kho Mob Liu Chen
Tshwj xeeb hauv kev cuam tshuam kev cuam tshuam tsawg kawg nkaus thiab kho cov txheej txheem rau cov qog raws li kev taw qhia duab
1. Microwave/Radiofrequency ablation
2. Percutaneous biopsy
3. Radioactive particle implantation
4. Kev tswj xyuas qhov mob
2. Lub hom phiaj thiab kev qhia txog kev kho mob ablative rau mob qog noj ntshav
Qhov "Cov Kws Paub Pom Zoo ntawm Kev Kho Mob Ablative for Primary and Metastatic Lung Tumors"(2014 ib tsab) faib cov kev kho ablative rau mob ntsws cancer rau hauv ob pawg: curative thiab palliative.
Curative ablationLub hom phiaj kom tiav necrotize cov qog nqaij hlav hauv zos thiab tuaj yeem ua tiav cov nyhuv curative.Mob qog noj ntshav thaum ntxov yog qhov qhia meej rau kev kho mob ablative,tshwj xeeb tshaj yog rau cov neeg mob uas tsis muaj zog cardiopulmonary muaj nuj nqi, muaj hnub nyoog siab tshaj, tsis muaj peev xwm zam kev phais, tsis kam mus rau kev phais resection, los yog cov neeg uas muaj ib tug qog recurrence tom qab conformal radiotherapy, raws li zoo raws li ib co cov neeg mob uas muaj ntau yam mob cancer ntawm lub ntsws uas yuav tsum tau khaws cia lub ntsws muaj nuj nqi. .
Palliative ablationaim rauQhov siab tshaj plaws ntawm cov qog nqaij hlav hauv cov neeg mob uas muaj mob qog noj ntshav siab theem siab, txo cov qog nqaij hlav, txo cov tsos mob los ntawm cov qog, thiab txhim kho tus neeg mob lub neej zoo.Rau cov neeg mob uas muaj mob qog noj ntshav theem siab, cov qog uas muaj qhov siab tshaj plaws> 5 cm lossis nrog ntau qhov txhab tuaj yeem ua rau ntau lub koob, ntau qhov taw qhia, lossis ntau qhov kev kho mob, lossis ua ke nrog lwm txoj kev kho mob kom muaj sia nyob ntev.Rau cov mob qog nqaij hlav hauv nruab nrab ntawm lub ntsws metastases, yog tias kev tswj hwm ntawm cov qog nqaij hlav extrapulmonary yog qhov zoo thiab tsuas yog qee qhov ntawm cov kab mob metastatic seem nyob hauv lub ntsws, kev kho ablative tuaj yeem pab tswj tus kab mob thiab txhim kho tus neeg mob lub neej zoo.
3. Qhov zoo ntawm kev kho ablative
Minimally invasive phais, rov qab sai: Ablative therapy yog suav tias yog ib qho kev phais mob me me.Lub ablative electrode koob siv feem ntau muaj ib txoj kab uas hla1-2 hli, ua rau me me phais incisions qhov loj ntawm ib rab koob qhov.Txoj kev no muaj qhov zoo xws likev raug mob tsawg kawg nkaus, mob tsawg, thiab rov qab sai dua.
Lub sijhawm phais luv luv, kev paub zoo:Ablative therapy feem ntau ua nyob rau hauv cov tshuaj loog hauv zos los yog ua ke nrog cov tshuaj loog, tshem tawm qhov xav tau ntawm endotracheal intubation.Cov neeg mob nyob hauv lub teeb pw tsaug zog thiab tuaj yeem tsim tau yooj yim nrog tus kais dej.Qee tus neeg mob yuav xav zoo li qhov kev phais tiav tom qabnap ceev.
Simultaneous biopsy rau kev kuaj mob kom raug:Thaum lub sij hawm kho ablative, ib coaxial kev taw qhia los yog synchronous puncture biopsy ntsuas yuav siv tau kom tau ib tug biopsy ntawm qhov txhab.Tom qab ntawdpathological kuaj thiab kuaj genetic testmuab cov ntaub ntawv tseem ceeb rau kev txiav txim siab kho mob tom ntej.
Cov txheej txheem rov ua dua: Ntau qhov kev tshawb fawb los ntawm ob qho tib si hauv tsev thiab thoob ntiaj teb tau pom tias kev tswj hwm hauv cheeb tsam ntawm cov neeg mob qog noj ntshav thaum ntxov uas tau txais kev kho mob ablative yog piv rau kev phais phais lossis kev kho hluav taws xob stereotactic.Nyob rau hauv cov ntaub ntawv ntawm lub zos recurrence, ablative therapytuaj yeem rov ua ntau zauskom rov tswj tau tus kab mob thaumua kom tus neeg mob lub neej zoo.
Ua kom lossis txhim kho kev tiv thaiv kab mob: Ablative therapy aims mustua cov qog nqaij hlav hauv lub cev, thiab qee zaum, nws tuaj yeem qhib lossis txhim kho tus neeg mob lub cev tsis muaj zog, ua rau a qhov uas tsis kho cov qog nyob rau hauv lwm qhov chaw ntawm lub cev qhia regression.Tsis tas li ntawd, kev kho ablative tuaj yeem ua ke nrog cov tshuaj siv los tsimib tug synergistic nyhuv.
Ablative therapy yog tshwj xeeb tshaj yog haum rau cov neeg mob uas tsis tuaj yeem zam kev phais phais lossis kev siv tshuaj loog vimkev ua haujlwm tsis zoo ntawm cardiopulmonary, hnub nyoog dhau los, lossis ntau yam hauv qab comorbidities.Nws kuj yog ib qho kev kho mob nyiam rau cov neeg mob nrogThaum ntxov-theem ntau nodules (xws li ntau lub hauv av-iav nodules).
Post lub sij hawm: Aug-23-2023