Kev kho thib tsib rau cov qog - Hyperthermia
Thaum nws los txog rau kev kho mob qog, tib neeg feem ntau xav txog kev phais, kws khomob, thiab kev kho hluav taws xob.Txawm li cas los xij, rau cov neeg mob qog noj ntshav theem siab uas tau poob txoj hauv kev rau kev phais lossis leej twg ntshai lub cev tsis txaus ntseeg ntawm kev siv tshuaj khomob lossis kev txhawj xeeb txog hluav taws xob los ntawm kev kho hluav taws xob, lawv txoj kev kho mob thiab lub sijhawm muaj sia nyob yuav raug txwv.
Hyperthermia, ntxiv rau kev siv los ua ib qho kev kho mob ib leeg rau cov qog, kuj tuaj yeem ua ke nrog kev kho mob, kev kho hluav taws xob, tshuaj suav tshuaj, thiab lwm yam kev kho mob los tsim cov organic complementarity.Nws ua rau kom cov neeg mob rhiab heev rau chemotherapy, kev kho hluav taws xob, thiab cov tshuaj suav tshuaj, uas ua rau muaj txiaj ntsig zoo dua tshem tawm cov qog qog hlwb.Hyperthermia txhim kho lub neej zoo thiab ua kom lub neej ntev ntawm cov neeg mob thaum txo cov kev mob tshwm sim los ntawm kev kho hluav taws xob thiab tshuaj khomob.Yog li ntawd, nws yog hu ua“Green therapy”los ntawm thoob ntiaj teb kev kho mob zej zog.
RF8 Hyperthermia System nrog Ultra-High-Speed Electromagnetic Waves
Thermotron-RF8yog lub qog hyperthermia uas tsim los ntawm Nyiv National Institute of Science thiab Technology, Kyoto University School of Medicine, thiab Yamamoto VINITA Corporation.
* RF-8 muaj ntau tshaj 30 xyoo ntawm kev kho mob.
* Nws siv lub ntiaj teb tshwj xeeb 8MHz electromagnetic yoj thev naus laus zis.
* Nws qhov kev tswj xyuas qhov kub thiab txias muaj qhov ua yuam kev tsawg dua + (-) 0.1 degrees Celsius.
Cov txheej txheem no tswj cov hluav taws xob hluav taws xob hluav taws xob zoo tsis tas yuav tsum muaj hluav taws xob tiv thaiv hluav taws xob.
Nws siv lub khoos phis tawj-pab tau zoo tsim rau kev npaj kho mob thiab saib xyuas thaum lub sijhawm kho.
Cov lus qhia rau Hyperthermia:
Lub taub hau thiab caj dab, Limbs:Mob taub hau thiab caj dab, malignant pob txha hlav, cov nqaij mos mos.
Cov kab mob thoracic:Mob ntsws cancer, esophageal cancer, cancer mis, malignant mesothelioma, malignant lymphoma.
Pelvic Cavity:Mob qog noj ntshav hauv lub raum, zais zis, mob qog nqaij hlav prostate, qog nqaij hlav qog nqaij hlav, mob qog noj ntshav hauv qhov chaw mos, mob qog noj ntshav, mob qog nqaij hlav endometrial, qog nqaij hlav zes qe menyuam.
Kab mob plab:Mob qog noj ntshav, mob plab, mob qog nqaij hlav pancreatic, mob qog nqaij hlav hauv plab.
Qhov zoo ntawm Hyperthermia ua ke nrog lwm cov kev kho mob:
Hyperthermia:Los ntawm cua sov cov ntaub so ntswg sib sib zog nqus nyob rau hauv lub hom phiaj rau 43 degrees Celsius, protein denaturation tshwm sim nyob rau hauv cov qog nqaij hlav cancer.Ntau yam kev kho mob tuaj yeem ua rau mob qog noj ntshav apoptosis thiab hloov pauv cov ntaub so ntswg hauv cheeb tsam thiab cov metabolism, ua rau muaj zog ntau ntxiv ntawm cov protein thiab cytokines, yog li txhawb kev tiv thaiv kab mob.
Hyperthermia + Tshuaj Kho Mob (Intravenous):Siv ib feem peb mus rau ib nrab ntawm cov tshuaj chemotherapy cov pa, synchronized intravenous tswj yog nqa tawm thaum lub cev kub mus txog 43 degrees Celsius.Qhov no txhim kho cov tshuaj hauv zos concentration thiab kev ua tau zoo thaum txo cov tshuaj tua kab mob.Nws tuaj yeem sim ua "txo toxicity" chemotherapy xaiv rau cov neeg mob uas tsis haum rau kev kho mob ib txwm muaj vim lawv lub cev.
Hyperthermia + Perfusion (Thoracic thiab Abdominal Effusions):Kev kho mob kheesxaws ntsig txog pleural thiab peritoneal effusions yog qhov nyuaj.Los ntawm ib txhij ua hyperthermia thiab perfusing chemotherapeutic cov neeg ua haujlwm los ntawm cov kav dej, cov qog nqaij hlav cancer tuaj yeem raug rhuav tshem, txo cov kua dej ntau ntxiv thiab txo cov tsos mob ntawm tus neeg mob.
Hyperthermia + Radiation Therapy:Kev kho hluav taws xob tsis tshua muaj txiaj ntsig zoo rau cov hlwb hauv theem S, tab sis cov hlwb no nkag siab rau cov cua sov.Los ntawm kev sib txuas hyperthermia li ntawm plaub teev ua ntej lossis tom qab kev kho hluav taws xob, kev kho mob tuaj yeem ua kom ntseeg tau rau txhua lub hlwb ntawm ntau theem ntawm lub voj voog ntawm tes nyob rau tib hnub, uas ua rau muaj peev xwm 1/6 txo cov hluav taws xob ntau.
Cov Ntsiab Cai thiab Keeb Kwm ntawm Kev Kho Mob Hyperthermia
Lo lus "Hyperthermia" los ntawm Greek lo lus, txhais tau tias "siab kub" lossis "overheating."Nws yog hais txog ib txoj kev kho mob uas sib txawv ntawm cov cua sov (radiofrequency, microwave, ultrasound, laser, thiab lwm yam).Hyperthermia tsis tsuas yog tua cov qog hlwb xwb tab sis kuj cuam tshuam kev loj hlob thiab kev loj hlob ib puag ncig ntawm cov qog hlwb.
Tus tsim ntawm hyperthermia tuaj yeem taug qab mus rau Hippocrates 2500 xyoo dhau los.Los ntawm txoj kev loj hlob ntev, ntau qhov xwm txheej tau sau tseg hauv cov tshuaj niaj hnub uas cov qog ploj lawm tom qab cov neeg mob kub taub hau.Xyoo 1975, ntawm International Symposium ntawm Hyperthermia nyob rau hauv Washington, DC, hyperthermia tau lees paub tias yog txoj kev kho thib tsib rau cov qog nqaij hlav malignant.Nws tau txais ntawv pov thawj FDA xyoo 1985.Hauv xyoo 2009, Suav Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau tshaj tawm "Kev Tswj Xyuas Tshwj Xeeb rau Cov qog qog ntshav hauv zos Hyperthermia thiab cov thev naus laus zis tshiab," txhim kho hyperthermia yog ib qho tseem ceeb rau kev kho mob qog noj ntshav, nrog rau kev phais, kev kho hluav taws xob, tshuaj khomob, thiab kev tiv thaiv kab mob.
Case Review
Case 1: Tus neeg mob nrog daim siab metastasis los ntawm lub raum cell carcinomaunderwent immunotherapy rau 2 xyoos thiab tau txais tag nrho ntawm 55 kev sib koom ua ke ntawm hyperthermia.Tam sim no, cov duab qhia tau hais tias qhov ploj ntawm cov qog, cov cim qog tau txo qis mus rau qhov qub, thiab tus neeg mob qhov hnyav tau nce los ntawm 110 phaus mus rau 145 phaus.Lawv tuaj yeem ua lub neej zoo ib yam.
Case 2: Tus neeg mob pulmonary mucinous adenocarcinomaCov kev mob tshwm sim tom qab kev phais, kev kho hluav taws xob, kev kho mob, thiab kev tiv thaiv kab mob.Cov qog nqaij hlav tau nthuav dav metastasis nrog pleural effusion.Kev ua kom ceev ion therapy ua ke nrog kev tiv thaiv kab mob siab heev tau pib peb lub lis piam dhau los.Cov kev kho mob tsis pom muaj kev phiv, thiab tus neeg mob tsis muaj qhov tsis xis nyob.Qhov kev kho mob no sawv cev rau tus neeg mob lub caij nyoog kawg.
Case 3: Postoperative mob qog nqaij hlav hauv plableej twg yuav tsum tsis txhob siv txoj kev kho mob vim kev puas tsuaj ntawm daim tawv nqaij.Tom qab ua tiav ib qho kev kho mob siab ceev ion, tus neeg mob tau txais 11phaus hauv qhov hnyav.
Post lub sij hawm: Aug-04-2023