Thaum Lub Xya Hli 31, 2025, ImmuneOnco Biopharmaceuticals tshaj tawm cov ntaub ntawv kev nyab xeeb thiab kev ua tau zoo thawj zaug los ntawm Theem 2 qhib-daim ntawv lo, ntau lub chaw kawm ntawm IMM2510 ua ke nrog kev kho mob chemotherapy rau cov neeg mob pem hauv ntej uas muaj mob qog noj ntshav tsis yog me me (NSCLC) ua nyob rau hauv Suav teb.
Txij li thaum Lub Xya Hli 1, 2025, muaj 33 tus neeg mob tau noj tshuaj ntawm 10 mg/kg, nrog rau 21 tus neeg mob uas muaj tsawg kawg ib qho kev ntsuam xyuas qog nqaij hlav (kev ntsuas tau zoo). Cov lus teb ib nrab tau pom hauv 62% ntawm cov neeg mob uas ntsuas tau zoo, suav nrog cov lus teb ib nrab hauv 80% (8/10) ntawm cov neeg mob uas muaj NSCLC squamous thiab 46% (5/11) ntawm cov neeg mob uas tsis yog NSCLC squamous. Feem ntau ntawm cov neeg mob uas ntsuas tau zoo tsuas muaj ib qho kev ntsuam xyuas qog nqaij hlav thaum cov ntaub ntawv txiav tawm. ImmuneOnco xav tias yuav nthuav tawm cov ntaub ntawv kev nyab xeeb thiab kev ua tau zoo hauv kev sim tshuaj kho mob IMM2510 hauv NSCLC pem hauv ntej ntawm lub rooj sib tham kho mob yav tom ntej.
Daim ntawv qhia txog kev nyab xeeb ntawm IMM2510 txhawb nqa kev txhim kho ntxiv hauv kev kho mob, tsis muaj kev txwv tshuaj lom hauv 33 tus neeg mob uas ntsuas tau kev nyab xeeb. Hauv cov neeg mob no, tsis muaj cov xwm txheej tsis zoo ntsig txog kev kho mob (TRAE) ua rau txo cov tshuaj lossis tuag, thiab tsuas yog ib qho TRAE ua rau tsum tsis txhob siv tshuaj. Cov TRAE Qib 3+ feem ntau yog cov ntshav, nrog rau cov kev mob tshwm sim tsis tshua muaj. Cov xwm txheej tsis zoo feem ntau cuam tshuam nrog VEGF inhibition (piv txwv li, ntshav siab, proteinuria, hemoptysis) thiab cov xwm txheej tsis zoo ntsig txog kev tiv thaiv kab mob tsis tshua muaj thiab feem ntau qis, thiab cov tshuaj tiv thaiv kab mob yuav luag txhua qib qis.
Tam sim no, tseem muaj ntau qhov kev sim tshuaj kho mob qog noj ntshav tshiab hauv Suav teb nrhiav cov neeg mob. Kev sab laj txog cov tshuaj tshiab thiab cov thev naus laus zis, koj tuaj yeem tiv tauj Beijing South Region Oncology Hospital International Department.
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Lub sijhawm tshaj tawm: Lub Yim Hli-05-2025